Federal update: DOJ partially rescheduled medical cannabis to Schedule III (April 28, 2026 final order). State-licensed medical operators may apply for expedited DEA registration through June 27, 2026; DEA hearing on full rescheduling set for June 29, 2026.

SC Cannabis Official Sources

South Carolina cannabis-related state agencies, statutes, and regulatory programs are distributed across the SC Department of Public Health (DPH, formerly DHEC, restructured 2025), the SC Department of Agriculture (SCDA) hemp program, the SC Law Enforcement Division (SLED), the Attorney General’s Office, and the SC General Assembly. Statutory framework lives in S.C. Code Title 44 Chapter 53 (controlled substances), Title 46 Chapter 55 (hemp), Title 56 Chapter 5 (DUI).

Last verified: May 2026

South Carolina State Agencies

SC Department of Public Health (DPH)

  • Website: dph.sc.gov.
  • Status: formerly the SC Department of Health and Environmental Control (DHEC); restructured in 2025 into separate DPH (public health) and Department of Environmental Services (DES). Cannabis-related responsibilities sit with DPH.
  • Cannabis-related responsibilities: would administer any future Compassionate Care Act medical program; current limited Julian’s Law CBD-only registry administration.

SC Department of Agriculture (SCDA)

  • Website: agriculture.sc.gov/hemp.
  • Phone: (803) 734-8339.
  • Hemp Program Coordinator: William R. Attaway, wattaway@scda.sc.gov.
  • Cannabis-related responsibilities: SC industrial hemp program under USDA-approved state plan; cultivation + processing licensing; sample testing; regulatory compliance.

SC Law Enforcement Division (SLED)

  • Website: sled.sc.gov.
  • Cannabis-related responsibilities: cannabis-related investigations; AG Wilson’s Operation Ganjapreneur enforcement coordination; SLED forensics laboratory drug-testing; civil-asset-forfeiture coordination; major drug-trafficking investigations.

SC Attorney General’s Office

  • Attorney General: Alan Wilson (R, in office since January 2011).
  • Website: scag.gov.
  • Cannabis-related responsibilities: cannabis-statute interpretation guidance; Operation Ganjapreneur hemp-derived intoxicant enforcement campaign (since approximately 2024); coordination with SLED and county law enforcement.

SC Board of Pharmacy

  • Website: llr.sc.gov/bop.
  • Cannabis-related responsibilities: dispensing regulation if Compassionate Care Act passes; current pharmacy-license oversight.

SC General Assembly

  • Website: scstatehouse.gov.
  • Senate: composition shapes Davis Compassionate Care Act prospects.
  • House: Speaker Murrell Smith’s gatekeeping has produced "House 3M death" of medical-cannabis bills.
  • Bill tracking: scstatehouse.gov/billsearch.php.

Statutory Framework

S.C. Code Title 44 Chapter 53 — Controlled Substances

  • § 44-53-370: possession, manufacture, distribution offenses; the PWID prima facie threshold (over 1 oz = PWID felony).
  • § 44-53-375: trafficking thresholds; 100-2,000 lbs = 25-year mandatory minimum.
  • § 44-53-391: paraphernalia (civil violation, $500 max civil fine).
  • §§ 44-53-1810 to 44-53-1830: Julian’s Law CBD-only carve-out for severe-epilepsy patients.

S.C. Code Title 46 Chapter 55 — Industrial Hemp

South Carolina Industrial Hemp Farming Act framework conformed to 2018 federal Farm Bill. SCDA administers licensing.

S.C. Code Title 56 Chapter 5 — Motor Vehicles

  • § 56-5-2930: DUI; impairment-based; no per se THC limit.
  • § 56-5-2950: implied consent.

S.C. Code Title 12 Chapter 21 — Drug Tax Stamp

Tax-stamp framework parallel to controlled-substance prosecution.

Constitutional Provisions

  • S.C. Const. art. XVI: ballot-initiative process. South Carolina has NO citizen ballot initiative — constitutional amendments must be referred by the General Assembly via two-thirds House and Senate vote. Statutory ballot initiatives also require legislative referral.

Federal Sources

  • 21 U.S.C. § 841: federal manufacture, distribution, possession with intent.
  • 21 U.S.C. § 844: federal simple possession.
  • 2018 Farm Bill (P.L. 115-334): hemp definition (≤0.3% delta-9 THC dry weight).
  • April 28, 2026 DOJ Schedule III rescheduling: 91 Fed. Reg. 22714.
  • PL 119-37 § 781: federal hemp 0.4 mg/package cap effective November 12, 2026.

Federal Agencies

  • DEA Atlanta Field Division oversees South Carolina.
  • U.S. Attorney’s Office, District of South Carolina: Charleston, Columbia, Florence, Greenville divisions.
  • USDA Agricultural Marketing Service: approves state hemp plans.
  • FDA: regulates CBD product labeling.

Federal Installations

  • Fort Jackson (Columbia): U.S. Army basic combat training; ~50,000 trainees per year.
  • MCRD Parris Island (Beaufort): U.S. Marine Corps recruit training.
  • Naval Base Charleston: SPAWAR (now NAVWAR) operations; nuclear power training.
  • Shaw AFB (Sumter): 20th Fighter Wing F-16C/D operations.
  • Joint Base Charleston: 437th + 315th Airlift Wings (Air Force / Navy joint base).

Related on this site: SC Cannabis Advocacy, Send a Message, Contact CannabisSouthCarolina.org.